Two stunning strikes, one in each half from Matthew Tipton and Hamza Bencherif earned Macclesfield a well deserved first victory of the season.
Vale threatened in parts but a hungry home side looked good value for the three points in a game which was delayed for ten minutes due to crowd congestion.
Tipton, the Silkmen's record Football League goalscorer, broke the deadlock after just six minutes collecting Carl Tremarco's ball into his feet and swivelling onto his right foot before arrowing a curling drive into the far corner from 25 yards.
Matthew Tipton - Showed he can still produce the goods at this level with a fabulous strike
He snatched at a chance minutes later to add a second when he scuffed a left footed effort to keeper Chris Martin and at the other end Shaun Brisley had to head a dangerous Tom Fraser corner out from under his own crossbar.
Macc wasted a great opportunity when they broke quickly three against two but Colin Daniel couldn't find Izak Reid's speedy burst forward through the centre.
Vale's Marc Richards, who once hit four goals in one game at the Moss Rose, struck a free kick into the wall and on 21 minutes Robert Taylor ran the length of the pitch before supplying Doug Loft who scooped his effort well over from ten yards.
The game continued at a frenetic pace with action at both ends, although as the half wore on it was Vale who looked the more likely to strike next.
Bencherif was booked for dissent after Lee Bell's foul on the edge of the box and Daniel's name also went into the book for trying to block a long throw.The majority of the Vale danger came down the wings with crosses by Kris Taylor on one flank and the long throws of Sam Stockley troublesome on the other.
However Macc dealt well with any spells of pressure and it looked as if only a mistake from the home backline would give Vale a way back into the game as the half time whistle blew.
Stockley's throw from the right caused havoc in the home penalty area on 54 minutes as it eventually ricocheted off Bencherif at the near post who knew little about it as it bounced wide for a corner.From the set piece Morgan headed behind again under pressure at the far post and then from the next substitute Claus Jorgensen sliced a shot horribly wide with his first touch of the evening.
On the hour Taylor looked to be away down the left but nobody could reach his cross cut back and when Izak Reid raced away on the counter attack he was crudely blocked by skipper Fraser who was booked.
The visitors pressed forward, buoyed by their large away following behind the goal but couldn't find a leveller and on 67 minutes the Silkmen doubled their advantage.Ben Wright challenged keeper Martin to Tipton's cross from the right and the ball broke to Bencherif who hit a thunderous volley which cannoned back off the underside of the bar. A few protested that it had crossed the line but the ball was only half cleared back to the Algerian who slammed a first time effort back into the opposite corner for his first goal for the club.
Hamza Bencherif - Had a great game in his first competitive outing in midfield and capped a great performance with the important second goal
More good touches from the big midfielder gave him space for another strike soon after, but he failed to strike it cleanly and his right footed curler was easily held by Martin.
The second goal knocked the wind out of Vale's sails and despite pumping more balls forward and committing more men to the front line Brain's goal was rarely tested.The Silkmen sat back on their two goal lead and seemed happy to run the clock down whenever they regained possession.
Loft's long range free kick found a way through the Macc wall and whistled inches past the post with Brain beaten on 84 minutes and the once packed away end was only half full by the time substitute Louis Dodds headed straight at the keeper at the back post.